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. 2019 Jan 10;42(6):790–800. doi: 10.1038/s41440-018-0197-z

Table 4.

The effects of Marukome shinki miso on urinary osmolality and free-water clearance

Group sOsm Uosm Cosm CH2O
Salt solution 299.8 ± 2.6 1988.7 ± 789.0 31.9 ± 11.4 −25.2 ± 7.1
Nenrin 298.4 ± 2.0 1766.7 ± 629.8 40.4 ± 9.5* −32.4 ± 6.8*
Shinki 298.3 ± 2.4 1794.2 ± 886.1 32.2 ± 7.1 −25.0 ± 7.5

Salt solution, group given salt solution; nenrin, Marukome Nenrin miso group; and shinki, Marukome shinki miso rich in ACE inhibitory activity miso group. Values are expressed as means ± SD (n = 10 in each group). Differences were assessed by one-way analysis of variance (ANOVA) followed by Fisher’s least significant difference post-hoc test (LSD test)

sOsm plasma osmolarity (mOsm/kg H2O), Uosm urinary osmolarity (mOsm/kg H2O), Cosm osmolarity clearance (mL/100 gBW/day), CH2O free-water clearance(mL/100 gBW/day)

*P < 0.05 vs salt solution group