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. 2020 Jan 6;52(1):106–117. doi: 10.1038/s41588-019-0559-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 10 — a–d, Pairwise similarity (PWS) matrices based on (a), all genome-wide protein-altering variants, (b), all venom gland-expressed genes, (c), core venom-ome genes, and (d), all 3FTx genes identified in this study. e, Distribution of protein altering variants in 106 venom gland-specific toxin genes. f, Distribution of protein altering variants in 3FTx genes located on chromosome 3 across all six study animals (NN01-NN06). Within each track in (b-f), homozygous variants are shown as blue vertical lines while heterozygous variants are shown as red vertical lines. NN01 and NN02 correspond to N. naja specimens obtained from Kerala, India. NN03, NN04, NN05 and NN06 correspond to N. naja specimens obtained from the Kentucky reptile zoo. MIC, microchromosomes.