. Author manuscript; available in PMC: 2022 May 1.

Published in final edited form as: Kidney Int. 2021 Jan 5;99(5):1118–1126. doi: 10.1016/j.kint.2020.12.023

Table 1.

Serum measurements after 18 weeks in GHS rats fed KCl, KCit, KCl+CTD or KCit+CTD with OH-proline.

solute	KCl	KCit	KCl+CTD	KCit+CTD
Sodium (mmol/L)	144.8 ± 0.7	142.7 ± 0.7	142.7 ± 0.5	141.5 ± 0.9^a
Potassium (mmol/L)	4.67 ± 0.13	4.44 ± 0.18	3.88 ± 0.17^a	3.73 ± 0.14^a,b
Chloride ( mmol/L)	100.4 ± 0.5	89.4 ± 8.9	95.3 ± 0.6	93.9 ± 0.6
Bicarbonate (mmol/L)	24.6 ± 0.5	24.8 ± 0.7	25.0 ± 0.4	26.4 ± 0.2
Calcium (mg/dL)	10.2 ± 0.08	10.2 ± 0.07	10.7 ± .06^a,b	10.6 ± 0.3^a,b
Phosphate (mg/dL)	5.56 ± 0.20	6.08 ± 0.40	5.97 ± 0.21	5.74 ± 0.22
Creatinine (mg/dL)	0.30 ± 0.01	0.30 ± 0.01	0.32 ± 0.01	0.32 ± 0.02

Results are mean ± SE for 9-10 rats/group.

p <0.05 vs KCl alone;

p<0.05 vs KCit alone.

There were no significant differences comparing KCl+CTD to KCit+CTD.