Figure 1:

Intrinsic plasticity is absent from SK2^−/− mice. (A) Top traces: in wild-type (WT) mice an increase in the spike count is triggered by a 5 Hz injection of depolarizing currents. Bottom traces: no excitability change is seen in SK2^−/−. Purkinje cells. (B) Time graph showing that intrinsic plasticity is triggered in WT (n = 7), but not in SK2^−/− Purkinje cells. The arrow indicates the time point of tetanization. Taken from Fig. 1, Grasselli et al., 2016, under the CC BY-NC-ND license.