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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Bone. 2021 Mar 16;147:115913. doi: 10.1016/j.bone.2021.115913

Table 2.

mCT cortical bone analysis

Males Females
γOTKO Ctrl γOTKO Ctrl
Mean SD Mean SD p value Mean SD Mean SD p value
T.Ar (mm2) 2.033 0.259 2.066 0.131 0.730 1.558 0.120 1.617 0.102 0.327
B.Ar (mm2) 0.722 0.116 0.691 0.031 0.411 0.553 0.046 0.570 0.031 0.415
M.Ar (mm2) 1.311 0.154 1.375 0.119 0.374 1.005 0.076 1.048 0.087 0.363
Ct.Th. (mm) 0.194 0.011 0.190 0.008 0.460 0.182 0.011 0.185 0.009 0.523
BMD (mg HA/cm3) 583.4 19.1 565.4 22.7 0.147 607.9 27.2 610.7 40.6 0.892
TMD (mg HA/cm3) 1048.9 12.5 1047.8 7.8 0.828 1048.5 9.1 1055.2 25.4 0.583
pMOI (mm4) 0.222 0.045 0.224 0.018 0.879 0.128 0.016 0.136 0.017 0.381
Imax/Cmax (mm3) 0.180 0.027 0.176 0.011 0.670 0.111 0.014 0.115 0.012 0.623
Imin/Cmin (mm3) 0.133 0.020 0.135 0.009 0.781 0.094 0.008 0.099 0.009 0.309

T.Ar – total area, B.Ar – bone area, M.Ar – marrow area, Ct.Th – cortical thickness, BMD – bone mineral density, TMD – tissue mineral density, pMOI – polar moment of inertia or torsional strength, Imax/Cmax - bending strength across the bone along the maximal centroid-to-edge distance, Imin/Cmin - bending strength across the bone along the minimal centroid-to-edge distance