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. 2021 Apr 26;11:8930. doi: 10.1038/s41598-021-88371-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Ultra-wide field scanning laser ophthalmoscopy (UWF) and Spectral Domain Optical Coherence Tomography (SD-OCT) images of patients who experienced floater for the first time in their life. (A) PVD stage 1. 59 year-old male. No definite change was noticed around optic disc in UWF. Note subtle change which is presenting the initiation of PVD (Posterior Vitreous Detachment, white arrow). (B) PVD stage 2. 60 year-old female. No definite change was noticed around optic disc in UWF. In the macular SD-OCT image, perifoveal posterior vitreous detachment (PVD) is in progress (white arrows) remaining posterior vitreous attached to fovea. In glaucomatous SD-OCT, PVD is in progress in some part of the optic disc margin (arrow), while most of the optic disc remains attached to the vitreous body. (C) PVD stage 3. 61 year-old male. Note two pVOs (peripapillary vitreous opacity, white arrows) noticed around the optic disc. In the macular SD-OCT image, PVD occurred throughout the entire macula. In the glaucomatous SD-OCT image, PVD is in progress while about half of the optic disc margin is detached to the vitreous body (a wide bidirectional arrow). (D) PVD stage 4. 66 year-old female. Note a dense pVO (white arrow) resembling a Weiss ring. In the macular SD-OCT image, reflectivity of vitreous body is not observed in hollow vitreous cavity. In glaucomatous SD-OCT image, reflectivity of vitreous body is not observed either. A shadow of pVO (arrow) is identified.