Table 1.
Clinical characteristics of 93 ALL patients.
| Childhood | Adult | |
|---|---|---|
| Sex | ||
| Male | 35 | 10 |
| Female | 30 | 18 |
| Diagnosis | ||
| B-ALL, NOS | 25 | 8 |
| B-ALL with t(9;22)(q34.1;q11.2); BCR-ABL1 | 2 | 11 |
| B-ALL with t(v;11q23.3); KMT2A rearranged | 4 | 1 |
| B-ALL with t(12;21)(p13.2;q22.1); ETV6-RUNX1 | 9 | |
| B-ALL with hyperdiploidy | 16 | 1 |
| B-ALL with t(1;19)(q23;p13.3); TCF3-PBX1 | 2 | 2 |
| T-ALL | 5 | 5 |
| Early T-cell precursor acute leukemia | 2 | |
| Cytogenetic risk group (B-ALL) | ||
| Good | 26 | 2 |
| Intermediate | 26 | 9 |
| High | 6 | 12 |
| 65 | 28 | |
(1) good risk—ETV6-RUNX1 and high hyperdiploidy (51–65 chromosomes); (2) intermediate risk—TCF3-PBX1, IGH translocations, B-other (none of these established abnormalities); (3) high risk—BCR-ABL1, KMT2A translocations, near haploidy (30–39 chromosomes), low hypodiploidy (less than 30 chromosomes), iAMP21, TCF3-HLF.