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. 2021 Apr 26;11:8897. doi: 10.1038/s41598-021-88170-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in blood pressure by allocation group and biochemically validated medication adherence. Vertical axis shows the changes in systolic blood pressure. Lower numbers indicate reduction in systolic blood pressure. The horizontal axis shows the changes on biochemically validated treatment adherence. Improved total adherent is represented at level of 0.00, partially adherent at level of − 1.00 and total nonadherence at level of − 2.00. The green line is the fitted regression line for the control group, the blue line is the fitted regression line for the intervention group. The dots show the units of measure for each of the intervention or the control group. The direction of the lines shows the association between changes in systolic blood pressure and changes in treatment adherence.