Table 2.

“Disease Perturbations from GEO down/up” category of Enrichr for 52 genes selected by applying PCA-based unsupervised FE to gene expression profiles. Six hypoxia experiments with adjusted P-values less than 0.05 are listed.

Term	Overlap	P-value	Adjusted P-value
Disease perturbations from GEO down
Hypoxia C0242184 human GSE4630 sample 250	13/349	$3.83\times {10}^{-12}$	$2.19\times {10}^{-11}$
Hypoxia C0242184 mouse GSE3195 sample 70	10/328	$1.05\times {10}^{-8}$	$3.77\times {10}^{-8}$
Hypoxia C0242184 human GSE4483 sample 440	9/275	$3.38\times {10}^{-8}$	$1.11\times {10}^{-7}$
Disease perturbations from GEO up
Hypoxia C0242184 human GSE4483 sample 440	27/325	$5.48\times {10}^{-35}$	$9.19\times {10}^{-33}$
Hypoxia C0242184 human GSE4630 sample 250	10/251	$8.07\times {10}^{-10}$	$2.38\times {10}^{-9}$
Hypoxia C0242184 mouse GSE3195 sample 70	10/272	$1.76\times {10}^{-9}$	$5.01\times {10}^{-9}$