Table 7.

“Disease Perturbations from GEO down/up” category of Enrichr for 53 genes (based on gene expression) and 200 genes (based on m6A) selected by applying KTD-based unsupervised FE to integration of gene expression and m6A profiles. Nine hypoxia experiments with adjusted P-values less than 0.05 are listed.

Term	Overlap	P-value	Adjusted P-value
Gene expression
Disease perturbations from GEO down
Hypoxia C0242184 human GSE4630 sample 250	15/349	$1.08\times {10}^{-14}$	$7.85\times {10}^{-14}$
Hypoxia C0242184 mouse GSE3195 sample 70	12/328	$4.53\times {10}^{-11}$	$2.03\times {10}^{-10}$
Hypoxia C0242184 human GSE4483 sample 440	10/275	$2.38\times {10}^{-9}$	$8.67\times {10}^{-9}$
Disease perturbations from GEO up
Hypoxia C0242184 human GSE4483 sample 440	27/325	$1.10\times {10}^{-34}$	$1.15\times {10}^{-32}$
Hypoxia C0242184 mouse GSE3195 sample 70	10/272	$2.14\times {10}^{-9}$	$5.79\times {10}^{-9}$
Hypoxia C0242184 human GSE4630 sample 250	9/251	$1.83\times {10}^{-8}$	$4.51\times {10}^{-8}$
m6A
Disease perturbations from GEO up
Hypoxia C0242184 human GSE4483 sample 440	30/325	$1.91\times {10}^{-20}$	$1.60\times {10}^{-17}$
Hypoxia C0242184 mouse GSE3195 sample 70	21/272	$4.63\times {10}^{-13}$	$1.94\times {10}^{-10}$
Hypoxia C0242184 human GSE4630 sample 250	17/251	$6.56\times {10}^{-10}$	$4.24\times {10}^{-8}$