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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: J Neurochem. 2020 Nov 16;157(4):1013–1031. doi: 10.1111/jnc.15226

Figure 5. Integrated Analysis.

Figure 5

A) Venn diagram demonstrating the number of mRNA transcripts (red), proteins (green), and phosphorylated proteins (blue) differentially expressed between lines and the overlap between each dataset. B) The correlation between mRNA and protein log2 FC and AR, respectively for the overlapping 87 mRNA transcripts and proteins differentially expressed between lines. Venn diagrams representing the overlapping, enriched GO terms discovered across all three omics analyses including C) biological processes, D) molecular function, and E) cellular component. Enriched F) Reactome and G) KEGG pathways discovered from both the proteomics and phosphoproteomic analysis. See supplementary table 1 for the associated overlapping genes, proteins, and phosphorylated proteins, and supplementary table 2 for the overlapping GO terms and pathways enriched