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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: J Neurochem. 2020 Nov 16;157(4):1013–1031. doi: 10.1111/jnc.15226

Table 2. Top Five Hub Genes from RNA-Sequencing Analysis.

Hub gene analysis was performed on the network of significant differentially expressed genes using CytoScape software with the cytoHubba plugin. Hub genes are highlighted in orange text in Figure 2.

Gene Gene Name Log2(FC HAP/LAP) Degree MCC
Ubc Ubiquitin C −1.70 20 45
Hist2h2be Histone H2B type 2-E 0.51 10 22
C3ar1 C3a anaphylatoxin chemotactic receptor 0.65 10 128
Ccl6 C-C motif chemokine 6 0.79 9 246
Ccl9 C-C motif chemokine 9 1.02 9 246

FC, Fold change; MCC, maximal clique centrality.