Table 4. Top Five Hub Proteins from Proteomic Analysis.
Hub protein analysis was performed on the network of significant differentially expressed proteins using CytoScape software with the cytoHubba plugin. Hub proteins are highlighted in orange text in Figure 3.
Gene | UniProt Accession | Protein | Log2(AR HAP/LAP) | Degree | MCC |
---|---|---|---|---|---|
Trf | Q921I1 | Serotransferrin | −0.07 | 17 | 45362 |
Vamp3 | P63024 | Vesicle-associated membrane protein 3 | 0.09 | 13 | 40345 |
Cst3 | A2APX3 | Cystatin-C | −0.34 | 12 | 5160 |
Rab-5C | P35278 | Ras-related protein Rab-5C | 0.06 | 12 | 40324 |
Ykt6 | Q9CQW1 | Synaptobrevin homolog YKT6 | 0.07 | 12 | 45384 |
MCC, maximal clique centrality; AR, Abundance Ratio.