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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: J Neurochem. 2020 Nov 16;157(4):1013–1031. doi: 10.1111/jnc.15226

Table 5. Proteins of the Top 20 Differentially Expressed Phosphorylated Peptides.

All peptides are also TMT modified.

Gene UniProt Accession Protein Peptide Position in Master Protein Phosphorylations in Master Proteins (% localization probability if known) Log2(AR HAP/LAP)
Increased in HAP vs LAP
Ank2 Q8C8R3 Ankyrin-2 1815–1823 2xPhospho [S1816(100); S1819(100)] 2.79
Nefh P19246 Neurofilament heavy polypeptide 565–582 2xPhospho [S571(100); S577(100)] 1.75
Ank2 Q8C8R3 Ankyrin-2 3217–3235 3xPhospho [S3226(100); S3229(100); S3230(100)] 1.63
Ank2 Q8C8R3 Ankyrin-2 1812–1823 2xPhospho [S1816(100); S1819(100)] 1.14
Nefh P19246 Neurofilament heavy polypeptide 559–576 2xPhospho [S565(100); S571(100)] 1.00
Mapt A0A0A0MQC7 Microtubule-associated protein 57–72 1xPhospho [T58(99.7)] 0.98
Bicc1 G3X8S6 Bicaudal C homolog 1 807–819 1xPhospho [S814(50); S819(50)} 0.90
Sgip1 Q8VD37 SH3-containing GRB2-like protein 3-interacting protein 1 76–99 1xPhospho [S95(100)] 0.85
Bsn O88737 Protein bassoon 2858–2874 1xPhospho [S2860(100)] 0.81
Mical3 Q8CJ19 Protein-methionine sulfoxide oxidase MICAL3 515–520 1xPhospho [S517(100)] 0.81
Decreased in HAP vs LAP
Ank2 Q8C8R3 Ankyrin-2 3763–3783 1xPhospho [S3781(91.5)] −2.3
Wdr37 Q05BF4 WD repeat-containing protein 37 20–26 2xPhospho [S22(100); S24(100)] −1.39
Dlg1 D3Z3B8 Disks large homolog 1 479–494 1xPhospho [S492(100)] −1.39
Amph A0A0G2JEG8 Amphiphysin 495–509 1xPhospho [S504(100)] −1.28
Scg2 Q03517 Secretogranin-2 549–561 1xPhospho [S556(99.7)] −1.21
Naxe Q8K4Z3 NAD(P)H-hydrate epimerase 41–52 1xPhospho [T45(89.4)] −1.12
Exoc7 O35250 Exocyst complex component 7 281–290 1xPhospho [S283(100)] −1.1
Scg2 Q03517 Secretogranin-2 549–561 1xPhospho [S556(99.7)] −1.04
Srsf10 Q3TFP0 Serine/arginine-rich-splicing factor 10 119–126 2xPhospho [S121(100); S123(100)] −1.04
Tgoln1 Q62313 Trans-Golgi network integral membrane protein 1 126–160 3xPhospho [S130(0.6); S131(32.8); T132(32.8); T135(32.8) −0.99

AR, Abundance Ratio.