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. 2021 Apr 26;16:67. doi: 10.1186/s11671-021-03522-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Indirect toxicity of HAPs toward hWJ-MSCs. The viability of hWJ-MSCs indirectly cultured with HAPs was measured for a 24 and b 72 h. *P < 0.05; **P < 0.01 versus the control. The control group consisted of cells incubated in CM without HAPs treatment, and cell viability was normalized as a percentage of the control. Abbreviations: HAPs hydroxyapatite particles, m-HAP micro-sized HAP particles, hWJ-MSCs human umbilical cord Wharton’s jelly-derived mesenchymal stem cells