Table-2.
Groups | Treatment | Mean body weights | Tumor growth | |||
---|---|---|---|---|---|---|
W (g) | WI (%) | V ( mL) | VI (%) | |||
Group 1 | Normal control (mice feed on balanced ration without inoculation) | 24.9±0.3 | - | - | - | - |
Group 2 | Mice feed on 50 mg milk fat/mouse (1 mg CLA) daily for 28 days without inoculation | 25.0±0.3 | - | - | - | - |
Group 3 | Positive control (TTM) feed on balanced ration | 30.7±0.1 | 5.8±0.1* | 100.0 | 7.0±0.4* | 100.0 |
Group 4 | TTM feed on 50 mg milk fat/mouse (1 mg CLA) daily post-inoculation. | 28.6±0.1 | 3.7±0.2** | 36.2** | 4.4±0.2** | 37.1** |
Group 5 | TTM feed on 50 mg milk fat/mouse (1 mg CLA) daily 28 days pre-inoculation. | 28.1±0.1 | 3.1±0.2** | 46.6** | 3.2±0.1** | 54.3** |
The values expressed as mean±SE, W=Weight, WI=Weight inhibition, V=Volume, VI=Volume inhibition,
Significant at P<0.05 as compared with normal control group (Group 1),
Significant at P<0.05 as compared with EAC group (Group 3). CLA=Conjugated linoleic acid, EAC=Ehrlich ascites carcinoma, TTM=Tumor transplanted mice