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. 2021 Mar 20;14(3):696–708. doi: 10.14202/vetworld.2021.696-708

Table-2.

Effect of daily oral administration of milk fat rich in CLA on tumor growth in EAC inoculated mice.

Groups Treatment Mean body weights Tumor growth

W (g) WI (%) V ( mL) VI (%)
Group 1 Normal control (mice feed on balanced ration without inoculation) 24.9±0.3 - - - -
Group 2 Mice feed on 50 mg milk fat/mouse (1 mg CLA) daily for 28 days without inoculation 25.0±0.3 - - - -
Group 3 Positive control (TTM) feed on balanced ration 30.7±0.1 5.8±0.1* 100.0 7.0±0.4* 100.0
Group 4 TTM feed on 50 mg milk fat/mouse (1 mg CLA) daily post-inoculation. 28.6±0.1 3.7±0.2** 36.2** 4.4±0.2** 37.1**
Group 5 TTM feed on 50 mg milk fat/mouse (1 mg CLA) daily 28 days pre-inoculation. 28.1±0.1 3.1±0.2** 46.6** 3.2±0.1** 54.3**

The values expressed as mean±SE, W=Weight, WI=Weight inhibition, V=Volume, VI=Volume inhibition,

*

Significant at P<0.05 as compared with normal control group (Group 1),

**

Significant at P<0.05 as compared with EAC group (Group 3). CLA=Conjugated linoleic acid, EAC=Ehrlich ascites carcinoma, TTM=Tumor transplanted mice