Table 3.
Univariate and multivariate analysis on atrial fibrillation occurrence.
| Univariate | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Variable | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Age | 1.09 | 1.07–1.11 | <0.001 | |||
| Female sex | 0.50 | 0.29–0.87 | 0.01 | |||
| RYGB Surgery | 0.64 | 0.31–1.31 | 0.22 | |||
| Baseline BMI | 1.04 | 1.00–1.07 | 0.04 | 1.05 | 1.01–1.09 | 0.004 |
| DM | 2.95 | 1.72–5.05 | <0.001 | 0.91 | 0.45–1.85 | 0.8 |
| HTN | 3.45 | 1.74–6.84 | <0.001 | 0.76 | 0.31–1.83 | 0.5 |
| OSA | 2.85 | 1.69–4.79 | <0.001 | 1.51 | 0.84–2.71 | 0.1 |
| CHADS2 score | 2.12 | 1.72–2.60 | <0.001 | 2.20 | 1.56–3.12 | <0.0001 |
| Hyperlipidemia | 1.99 | 1.15–3.46 | 0.01 | |||
| CAD | 2.98 | 1.64–5.42 | <0.001 | |||
| Cardiomyopathy | 12.96 | 3.12–53.79 | <0.001 | |||
| CKD | 6.04 | 3.24–11.25 | <0.001 | |||
| Stroke | 1.11 | 0.41–3.02 | 0.83 | |||
| CHF | 9.49 | 5.18–17.41 | <0.001 | |||
| Statins | 1.75 | 1.04–2.95 | 0.04 | |||
| ACEI/ARB | 1.04 | 0.59–1.81 | 0.90 | |||
| CCB | 1.46 | 0.71–3.01 | 0.03 | |||
| BB | 1.43 | 0.78–2.63 | 0.25 | |||
| Diuretics | 2.25 | 1.32–3.83 | 0.003 | |||
| Insulin | 3.60 | 1.86–6.99 | <0.001 | |||
| Metformin | 0.94 | 0.37–2.35 | 0.89 | |||
| Aspirin | 1.45 | 0.84–2.50 | 0.19 | |||
| Digoxin | 44.25 | 13.31–147.11 | <0.001 | |||
| FBG | 1.01 | 1.00–1.01 | 0.01 | |||
| Cr | 2.23 | 0.60–8.30 | 0.23 | |||
| TG | 1.0 | 0.99–1.01 | 0.39 | |||
| HDL-C | 0.99 | 0.97–1.01 | 0.33 | |||
| LDL-C | 0.99 | 0.99–1.00 | 0.38 | |||
ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BB, β-blocker; BMI, body mass index; CAD, coronary artery disease; CCB, calcium channel blocker; CHADS2, congestive heart failure, hypertension, diabetes mellitus, prior stroke or transient ischemic attack; CHF, congestive heart failure; CKD, chronic kidney disease; Cr, creatinine; DM, diabetes mellitus; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; HR, hazard ratio; HTN, hypertension; LDL-C, low-density lipoprotein cholesterol; OSAS, obstructive sleep apnea syndrome; TG, triglyceride.