Table 3.
Comparison of cognition function and behavioral/psychiatric symptoms between both clusters of patients classified by their EEG powers for the three EEG sessions.
| Session 1 | Session 2 | Session 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Cluster 1 | Cluster 2 | P-value | Cluster 1 | Cluster 2 | P-value | Cluster 1 | Cluster 2 | P-value | |
| Demographic | |||||||||
| Age (years) | 76.9 ± 6.6 | 79.1 ± 6.8 | 0.176 | 76.6 ± 5.9 | 79.2 ± 7.3 | 0.105 | 76.4 ± 6.4 | 79.5 ± 6.8 | 0.058 |
| Sex, male (%) | 24.2 | 52.8 | 0.015 | 30.3 | 47.2 | 0.150 | 29.4 | 48.6 | 0.103 |
| Education (years) | 7.2 ± 5.3 | 8.6 ± 4.8 | 0.260 | 7.6 ± 4.7 | 8.2 ± 5.4 | 0.645 | 8.2 ± 4.7 | 7.6 ± 5.4 | 0.655 |
| Duration of illness (years) | 2.6 ± 2.6 | 2.1 ± 1.8 | 0.354 | 2.2 ± 2.5 | 2.5 ± 1.9 | 0.606 | 2.4 ± 2.4 | 2.2 ± 2.0 | 0.686 |
| Cognitive functioning | |||||||||
| MMSE | 17.9 ± 4.5 | 19.9 ± 5.7 | 0.104 | 18.3 ± 4.7 | 19.6 ± 5.7 | 0.278 | 17.9 ± 5.3 | 19.9 ± 4.9 | 0.095 |
| Verbal fluency | 8.8 ± 3.3 | 9.6 ± 3.4 | 0.370 | 8.5 ± 3.3 | 9.9 ± 3.3 | 0.087 | 8.5 ± 3.5 | 9.9 ± 3.0 | 0.074 |
| Digit forward | 8.4 ± 2.4 | 9.0 ± 2.5 | 0.359 | 8.4 ± 2.1 | 8.9 ± 2.7 | 0.336 | 8.4 ± 2.3 | 8.9 ± 2.6 | 0.341 |
| Digit backward | 3.6 ± 2.2 | 4.1 ± 2.0 | 0.374 | 3.6 ± 2.1 | 4.1 ± 2.1 | 0.374 | 3.7 ± 2.3 | 4.1 ± 2.0 | 0.440 |
| Neuropsychiatric Inventory | |||||||||
| Total score | 19.3 ± 18.6 | 10.0 ± 9.7 | 0.014 | 17.2 ± 18.9 | 11.9 ± 10.6 | 0.156 | 17.7 ± 18.7 | 11.3 ± 10.3 | 0.086 |
| Delusion | 1.4 ± 2.4 | 0.5 ± 1.0 | 0.040 | 1.1 ± 2.0 | 0.8 ± 1.7 | 0.573 | 1.0 ± 2.0 | 0.9 ± 1.7 | 0.851 |
| Hallucination | 0.8 ± 1.8 | 0.1 ± 0.3 | 0.040 | 0.7 ± 1.8 | 0.2 ± 0.4 | 0.089 | 0.6 ± 1.8 | 0.2 ± 0.5 | 0.192 |
| Agitation/aggression | 1.6 ± 2.3 | 0.8 ± 1.6 | 0.076 | 1.6 ± 2.3 | 0.8 ± 1.6 | 0.125 | 1.8 ± 2.5 | 0.6 ± 1.0 | 0.013 |
| Dysphoria/depression | 2.1 ± 2.7 | 1.1 ± 2.2 | 0.110 | 2.2 ± 3.0 | 1.0 ± 1.7 | 0.065 | 2.0 ± 3.0 | 1.1 ± 1.7 | 0.128 |
| Anxiety | 2.0 ± 3.0 | 0.5 ± 1.1 | 0.011 | 1.3 ± 2.5 | 1.1 ± 2.2 | 0.735 | 1.4 ± 2.5 | 1.0 ± 2.2 | 0.531 |
| Euphoria | 0.3 ± 1.0 | 0.1 ± 0.3 | 0.170 | 0.3 ± 1.0 | 0.1 ± 0.3 | 0.170 | 0.3 ± 1.0 | 0.1 ± 0.3 | 0.311 |
| Apathy | 2.0 ± 3.1 | 1.4 ± 2.2 | 0.351 | 2.2 ± 3.2 | 1.2 ± 2.1 | 0.118 | 2.1 ± 3.1 | 1.2 ± 2.2 | 0.159 |
| Disinhibition | 0.9 ± 2.1 | 0.8 ± 1.9 | 0.779 | 0.8 ± 2.0 | 0.9 ± 2.0 | 0.932 | 1.1 ± 2.3 | 0.7 ± 1.6 | 0.364 |
| Irritability | 1.9 ± 3.4 | 1.0 ± 2.2 | 0.191 | 2.1 ± 3.4 | 0.9 ± 2.0 | 0.085 | 2.3 ± 3.5 | 0.6 ± 1.6 | 0.013 |
| Aberrant motor behavior | 0.9 ± 1.9 | 1.2 ± 2.3 | 0.535 | 0.7 ± 1.4 | 1.3 ± 2.5 | 0.222 | 0.6 ± 1.3 | 1.5 ± 2.6 | 0.094 |
| Sleep change | 2.5 ± 3.4 | 1.1 ± 1.5 | 0.034 | 2.1 ± 3.3 | 1.5 ± 1.8 | 0.360 | 2.3 ± 3.4 | 1.3 ± 1.6 | 0.101 |
| Appetite change | 2.8 ± 4.1 | 1.4 ± 2.5 | 0.100 | 2.1 ± 3.6 | 2.0 ± 3.3 | 0.910 | 2.1 ± 3.6 | 2.1 ± 3.2 | 0.974 |
MMSE, Mini-Mental State Examination. P-values of <0.05 are considered statistically significant and shown in bold.