Table 2.
The numbers of sequences from the VDJdb and McPAS-TCR that match the CDR3 motifs of gluten-specific TCRs.
| VDJdb (n=67689) | McPAS-TCR (n=34795) | |||||
|---|---|---|---|---|---|---|
| CDR3α (n=28268) | CDR3β (n=39405) | CDR3α:CDR3β (n=22284) | CDR3α (n=11675) | CDR3β (n=13332) | CDR3α:CDR3β (n=7501) | |
| R-motif | – | 0 | – | – | 0 | – |
| Paired R-motif | – | – | 0 | – | – | 0 |
| NDYKLS-motif | 0 | – | – | 0 | – | – |
| Motifs at distance=1 | 4a | 1c | – | 21a | 3h | – |
| Motifs at distance=2 | 10b | 4d | 0e | 21g | 3i | 0e |
| Motifs at distance=4 | – | – | 0f | – | – | 0f |
aSequence match with 2 out of 38 CDR3α motifs.
bSequence match with 5 out of 37 CDR3α motifs.
cSequence match with 1 out of 25 CDR3β motifs.
dSequence match with 4 out of 32 CDR3β motifs.
eSequence match with 0 out of 18 CDR3α:CDR3β motifs.
fSequence match with 0 out of 27 CDR3α:CDR3β motifs.
gSequence match with 2 out of 37 CDR3α motifs.
hSequence match with 0 out of 25 CDR3β motifs.
iSequence match with 0 out of 32 CDR3β motifs.