Table 1.

Models and variables.

Model	Variable
Bivariate-model	TMB and PD-L1 expression
Tri-model	TMB, PD-L1 expression and MATH
Pathway-model	TMB, PD-L1 expression, MATH and immune-related pathways

TMB, tumor mutational burden; PD-L1, programmed cell death-ligand 1; MATH, mutant-allele tumor heterogeneity.