Skip to main content
. 2021 Apr 13;10:596623. doi: 10.3389/fonc.2020.596623

Figure 3.

Figure 3

CircZFR functionally targets miR-1270 and miR-545. (A) The putative binding sites between circ_0072088 and miR-1270, circ_0072088 and miR-545 were predicted. (B, C) Relative luciferase activity in bladder cancer (BCa) cells with or without miR-overexpression. (**P < 0.01 vs. miR-NC group, n = 3) (D) Quantification of miR-1270 and miR-545 expression by RNA pull-down assay in BCa cells. (*P < 0.01 vs. bio-NC group, n = 3) (E) MiR-1270 and miR-545 expression in BCa cells. (**P < 0.01 vs. sh-NC group, n = 3) (F) MiR-1270 and miR-545 expression in human tissues. (**P < 0.01 vs. adjacent normal tissue, n = 60) (G) Pearson correlation analyses between the expression of circZFR and miR-1270/miR-545.