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. 2021 Mar 13;24:646–657. doi: 10.1016/j.omtn.2021.03.009

Figure 3.

Figure 3

Blocking miR-410 prevents the development of atherosclerosis

(A) miR-410 expression in HUVECs treated with ox-LDL. (B) miR-410 expression in HUVECs after inhibiting miR-410. (C) HUVEC viability. (D) Colony formation to evaluate HUVEC viability. (E) HUVEC apoptosis. (F) The expression of TNF-α, IL-1, and IL-6 in HUVEC culture supernatant. (G) VCAM-1, ICAM-1, and MCP-1 levels in HUVECs; ∗p < 0.05. Measured data are described as mean ± standard deviation. Unpaired t test was used to analyze data between two groups and Bonferroni or Tukey’s test to analyze data among groups at different time points after repeated-measures ANOVA. All of the experiments were performed with technological triplicate.