Table 1.
Characteristics of the study population.
| Healthy | PCa | PCa+ADT | p | |
|---|---|---|---|---|
| (n = 56) | (n = 55) | (n = 59) | ||
| Age (years) | 68.77 (10.47) | 69.69 (9.22) | 77.90 (8.08)* | <0.001 |
| DBP (mmHg) | 72.51 (8.81) | 71.29 (9.66) | 74.12 (6.34) | NS |
| SBP (mmHg) | 126.15 (11.03) | 127.09 (10.14) | 131.02 (7.19)* | 0.01 |
| HR (bpm) | 73.25 (6.94) | 72.22 (7.83) | 75.78 (6.65)* | 0.03 |
| PSA (ng/ml) | 1.18 (0.52) | 1.13 (0.38) | 3.23 (2.49)*+ | 0.009 |
| FSH (mUI/ml) | 14.00 (12.66) | 10.67 (6.48) | 5.96 (7.66) *+ | <0.001 |
| LH (mUI/ml) | 7.99 (12.17) | 5.75 (3.57) | 1.04 (3.75)*+ | <0.001 |
| Test (pg/ml) | 6.22 (13.50) | 14.91 (6.74) | 1.89 (3.82)*+ | <0.001 |
| Estr (pg/ml) | 11.62 (29.50) | 32.20 (11.65) | 17.93 (9.54)*+ | <0.001 |
| Glucose (mg/dl) | 109.38 (25.71) | 111.85 (30.06) | 112.58 (32.44) | NS |
| Uric acid (mg/dl) | 6.25 (1.96) | 5.60 (1.22) | 5.00 (1.36)* | <0.001 |
| CRP (mg/dl) | 3.08 (3.88) | 3.12 (4.45) | 8.29 (26.48) | NS |
| TXA2 (pg/ml) | 13.02 (8.52) | 17.81 (11.06)* | 26.96 (43.78) * | <0.001 |
Values are expressed as mean with standard deviation in parentheses.
*
Statistical significance compared with healthy group.
+
Statistical significance compared with PCa group.
DBP, diastolic blood pressure; SBP systolic blood pressure; HR, heart rate; PSA, prostatic specific antigen; FSH, follicle-stimulating hormone; LH, luteinizing hormone; Test, testosterone; Estr, estradiol; CRP, C-reactive protein; TXA2, thromboxane A2.