Figure 7.

Correlations between tissue dopamine (DA) and noradrenaline (NA) levels, between tissue DA and plasma 3,4-dihydroxyphenylalanine (DOPA) levels, and between tissue DOPA and plasma DOPA levels.A–F, correlations between NA and DA levels in the heart (A), pancreas (B), stomach (C), lung (D), spleen (E), and kidney (F) of Th^fl/fl (Ctrl) and dopamine β-hydroxylase Cre-ERT2/Th^fl/fl (conditional KO [cKO]) at 2 or 4 weeks after tamoxifen injection. The y-axis represents the NA content, and the x-axis represents DA content, and the lines indicate the linear fitting. G–L, correlations between plasma DOPA and tissue DA levels in the heart (G), pancreas (H), stomach (I), lung (J), spleen (K), and kidney (L) of the Ctrl and cKO mice at 2 and 4 weeks. The y-axis represents DA contents, and the x-axis represents plasma DOPA levels. Lines indicate the linear fitting. M–R, correlations between plasma DOPA and tissue DOPA levels in the heart (M), pancreas (N), stomach (O), lung (P), spleen (Q), and kidney (R) of Ctrl and cKO mice at 2 and 4 weeks after tamoxifen injection. The y-axis represents DOPA contents, and the x-axis represents plasma DOPA levels. Lines indicate the linear fitting. Blue-colored points indicate Ctrl mice, orange-colored points indicate cKO mice, circle-shaped points indicate the 2 weeks, and triangle-shaped points indicate the 4 weeks. Pearson's correlation coefficients were shown in the plots.