Table 5. Key Features according to Different UIP Category on High-Resolution CT with Its Correspondence to ILA/NSIP.
Typical UIP [8, 9] | Probable UIP [8, 9] | Indeterminate for UIP [8, 9] | Most consistent with non-IPF [8, 9] | |
---|---|---|---|---|
Basal and subpleural predominant distribution | + | + | −; Variable/diffuse | |
Heterogeneity | + | + | ||
Distortion | + | + | Subtle | |
GGO | ± | ± | ||
Peripheral traction bronchiectasis or bronchiolectasis | + | + | - | |
Honeycombing | + | - | - | |
ILA defined by CT [10] | Subpleural | Subpleural | Non-Subpleural | |
Fibrotic ILA | Non-Fibrotic ILA | ILA | ||
NSIP defined by pathology [37] | Progressive NSIP | Fibrosing NSIP | Cellular NSIP |
GGO = ground-glass opacities, ILA = interstitial lung abnormality, IPF = idiopathic pulmonary fibrosis, NSIP = nonspecific interstitial pneumonia, UIP = usual interstitial pneumonia