Table 10. Summary of Recommendations and Evidence.
| Clinical Scenario | Modality | Appropriateness Category | Evidence Level | RRL |
|---|---|---|---|---|
| Known or suspected thyroid nodule, initial imaging | Neck US | Usually appropriate | I | 0 |
| Neck US with US-guided biopsy of thyroid nodule | Usually appropriate | I | 0 | |
| Neck CT without IV contrast | Usually not appropriate | II | ![]() |
|
| Neck CT with IV contrast | Usually not appropriate | II | ![]() |
|
| Neck CT with and without IV contrast | Usually not appropriate | II | ![]() |
|
| Neck MRI without IV contrast | Usually not appropriate | IV | 0 | |
| Neck MRI with and without IV contrast | Usually not appropriate | IV | 0 | |
| Preoperative evaluation of thyroid cancer | Neck US | Usually appropriate | I | 0 |
| US-guided biopsy and/or washout Tg for neck lymph node | Usually appropriate | I | 0 | |
| Neck CT without IV contrast | Usually not appropriate | II | ![]() |
|
| Neck CT with IV contrast | May be appropriate | II | ![]() |
|
| Neck CT with and without IV contrast | May be appropriate | II | ![]() |
|
| Neck MRI without IV contrast | Usually not appropriate | II | 0 | |
| Neck MRI with and without IV contrast | May be appropriate | II | 0 | |
| Chest CT without IV contrast | Usually not appropriate | IV | ![]() |
|
| Chest CT with IV contrast | May be appropriate | IV | ![]() |
|
| Chest CT with and without IV contrast | Usually not appropriate | IV | ![]() |
|
| Early imaging after surgery of DTC | Neck US | Usually appropriate | II | 0 |
| Neck CT without IV contrast | Usually not appropriate | IV | ![]() |
|
| Neck CT with IV contrast | May be appropriate | IV | ![]() |
|
| Neck CT with and without IV contrast | May be appropriate | IV | ![]() |
|
| Neck MRI without IV contrast | Usually not appropriate | IV | 0 | |
| Neck MRI with and without IV contrast | Usually not appropriate | IV | 0 | |
| Suspected recurrence of DTC | Neck US | Usually appropriate | II | 0 |
| US-guided biopsy and/or washout Tg | Usually appropriate | II | 0 | |
| Neck CT without IV contrast | Usually not appropriate | II | ![]() |
|
| Neck CT with IV contrast | May be appropriate | II | ![]() |
|
| Neck CT with and without IV contrast | May be appropriate | II | ![]() |
|
| Neck MRI without IV contrast | Usually not appropriate | II | 0 | |
| Neck MRI with and without IV contrast | May be appropriate | II | 0 | |
| Chest CT without IV contrast | May be appropriate | II | ![]() |
|
| Chest CT with IV contrast | May be appropriate | II | ![]() |
|
| Chest CT with and without IV contrast | Usually not appropriate | II | ![]() |
CT = computed tomography, DTC = differentiated thyroid carcinoma, IV = intravenous, MRI = magnetic resonance imaging, RRL = relative radiation level, Tg = thyroglobulin, US = ultrasonography

