Table 2. Comparison of CT and MR Imaging Features between Patients with IP and IP-SCC.
| IP-SCC (n = 21) | IP (n = 41) | P | Sensitivity (95% CI) | Specificity (95% CI) | C-statistics (95% CI) | |
|---|---|---|---|---|---|---|
| Bony erosion on CT, n (%) | 19 (91) | 14 (34) | < 0.001 | 58 (39–75) | 93 (77–99) | 0.753 (0.627–0.854) |
| Conventional MRI, n (%) | ||||||
| Tumor necrosis | 7 (33) | 0 (0) | < 0.001 | 100 (59–100) | 75 (61–85) | 0.873 (0.764–0.944) |
| Orbit invasion | 7 (33) | 0 (0) | < 0.0001 | 100 (59–100) | 75 (61–85) | 0.873 (0.764–0.944) |
| Soft tissue invasion other than orbit | 10 (48) | 1 (2) | < 0.0001 | 91 (59–100) | 78 (65–89) | 0.847 (0.733–0.926) |
| Intracranial invasion | 1 (5) | 0 (0) | 0.339 | NA | NA | NA |
| Loss of CCP* | < 0.001 | 95 (76–100) | 85 (71–94) | 0.903 (0.801–0.964) | ||
| Absent | 1 (5) | 35 (85) | ||||
| Partial | 10 (48) | 4 (10) | ||||
| Diffuse | 10 (48) | 2 (5) | ||||
| Diffusion-weighted imaging (SD), 10-3 mm2/sec | ||||||
| Mean ADC | 1.20 (0.18) | 1.51 (0.26) | < 0.001 | 81 (58–95) | 76 (60–88) | 0.832 (0.730–0.933) |
| ADC5 | 0.73 (0.17) | 0.92 (0.36) | < 0.001 | 90 (70–99) | 61 (45–76) | 0.754 (0.633–0.875) |
| ADC10 | 0.84 (0.15) | 1.09 (0.29) | < 0.001 | 86 (64–97) | 76 (60–88) | 0.810 (0.700–0.919) |
| ADC15 | 0.91 (0.16) | 1.20 (0.23) | < 0.001 | 90 (70–99) | 73 (57–86) | 0.861 (0.768–0.954) |
| ADC20 | 0.96 (0.16) | 1.30 (0.26) | < 0.001 | 90 (70–99) | 76 (60–88) | 0.884 (0.801–0.968) |
| ADC25 | 1.00 (0.17) | 1.36 (0.27) | < 0.001 | 90 (70–99) | 71 (55–84) | 0.877 (0.793–0.962) |
*Partial or diffuse loss of CCP was defined as test positivity. ADC = apparent diffusion coefficient, ADC5 = 5th percentile cutoff of ADC, ADC10 = 10th percentile cutoff of ADC, ADC15 = 15th percentile cutoff of ADC, ADC20 = 20th percentile cutoff of ADC, ADC25 = 25th percentile cutoff of ADC, CCP = convoluted cerebriform pattern, CI = confidence interval, CT = computed tomography, MRI = magnetic resonance imaging