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. 2021 Apr 22;15:1653–1666. doi: 10.2147/DDDT.S297500

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© 2021 Liu et al.

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FDCA inhibited hypoxia-induced activation of the intracellular Ca²⁺ signaling pathway. (A) Representative images of [Ca²⁺]_i. (B) Quantitative analysis of Fluo-4 AM fluorescence intensity. (C) Representative Western blot bands. (D) Quantitative analysis of CaMK II/p-CaMK II. (E) Quantitative analysis of p-MLCK/MLCK. Data are expressed as mean ± SD (n=3-5). *P<0.05, **P<0.01 vs normoxia control group; ^##P<0.01 vs hypoxia group; ^&P<0.05, ^&&P<0.01 vs hypoxia+FDCA group, ns (not significant).