Table 3. Annual changes in methicillin resistance and MLST sequence type among adult SAB patients.
| Characteristics | No. (%) of patients (n = 1,782) | Annual change (%) | P value | |||
|---|---|---|---|---|---|---|
| Methicillin resistance | ||||||
| MRSA | 924 (51.9) | −1.598 | 0.017 | |||
| Place of acquisition | ||||||
| Community-acquired nonhealthcare-associated | 251 (14.1) | 1.315 | 0.010 | |||
| Community-healthcare-associated | 540 (30.3) | 1.051 | 0.134 | |||
| Hospital-acquired | 991 (55.6) | −2.366 | 0.002 | |||
| Major MLST type (major corresponding spa types) according to methicillin resistance (n = 1,778) | ||||||
| MRSA (n = 921) | ||||||
| ST5 (t2460 [n = 298], t9353 [n = 56], t002 [n = 51]) | 538 (58.4) | −3.206 | < 0.001 | |||
| ST5/spa-t2460 | 298 (32.4) | −3.468 | 0.002 | |||
| ST5/spa-t9353 | 56 (6.1) | −0.501 | 0.093 | |||
| ST5/spa-t002 | 51 (5.5) | 0.276 | 0.273 | |||
| ST72 (t324 [n = 142], t664 [n = 44], t148 [n = 33]) | 299 (32.5) | 2.798 | < 0.001 | |||
| ST72/spa-t324 | 142 (15.4) | 0.773 | 0.074 | |||
| ST72/spa-t664 | 44 (4.8) | 0.249 | 0.363 | |||
| ST72/spa-t148 | 33 (3.6) | 0.232 | 0.182 | |||
| ST239 (t037 [n = 19]) | 26 (2.8) | −0.597 | < 0.001 | |||
| ST8 (t008 [n = 14]) | 18 (2.0) | 0.647 | 0.011 | |||
| ST8/spa-t008 | 14 (1.5) | 0.518 | 0.013 | |||
| MSSA (n = 857) | ||||||
| ST72 (t126 [n = 106]) | 161 (18.8) | 1.717 | 0.007 | |||
| ST72/spa-t126 | 106 (12.4) | 1.267 | 0.015 | |||
| ST188 (t189 [n = 116]) | 134 (15.6) | −1.188 | < 0.001 | |||
| ST188/spa-t189 | 116 (13.5) | −1.030 | 0.016 | |||
| ST30 (t338 [n = 15], t012 [n = 11]) | 74 (8.6) | −0.696 | 0.013 | |||
| ST15 (t084 [n = 16], t085 [n = 15]) | 71 (8.3) | 0.566 | 0.080 | |||
| ST1 (t127 [n = 46]) | 59 (6.9) | −0.585 | 0.146 | |||
| ST6 (t304 [n = 27]) | 55 (6.4) | −0.514 | 0.151 | |||
| ST5 (t688 [n = 11], t179 [n = 8]) | 41 (4.8) | −0.325 | 0.506 | |||
| ST8 (t008 [n = 18]) | 31 (3.6) | 0.454 | 0.027 | |||
| ST8/spa-t008 | 18 (2.1) | 0.395 | 0.021 | |||
MLST = multilocus sequence typing, SAB = Staphylococcus aureus bacteremia, MRSA = methicillin-resistant Staphylococcus aureus, MSSA = methicillin-susceptible Staphylococcus aureus.