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. 2021 Apr 13;11:610885. doi: 10.3389/fonc.2021.610885

Table 1.

IC50 values and their quotient (ratio of equivalence) as metrics for growth inhibition by FASN inhibitors Fasnall and G28UCM in A2780, OVCAR3, and SKOV3 OC cells as determined with a formazan dye assay.

A2780 OVCAR3 SKOV3
IC50 (µM) (Means ± SD)
Fasnall 55.1 ± 0.4 88.6 ± 3.4 105.0 ± 1.0
G28UCM 2.6 ± 1.7 4.5 ± 0.6 10.7 ± 5.8
Ratio of Equivalence (IC50 Fasnall/IC50 G28UCM)
Fasnall/G28UCM 21.2 19.7 9.8

Means ± SD of at least three independent experiments (for details see Materials and Methods section).