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. 2021 Apr 12;9(4):e24604. doi: 10.2196/24604

Table 4.

Slope coefficient estimates, 95% confidence intervals, z score statistics, and P values from 3-level linear mixed models on the entire dataset for exploring associations between sleep featuresa and the PHQ-8 score and sleep subscoreb.

Features PHQ-8c score Sleep subscore

Coeff.d 95% CI z score P value Coeff. 95% CI z score P value
Av_tst 0.013 0.006, 0.019 3.93 <.001 –0.004 –0.034, 0.025 –0.28 .78
Av_time_bed 0.016 0.009, 0.023 4.45 <.001 0.005 –0.028, 0.038 0.29 .77
Deep_pct –0.007 –0.026, 0.011 –0.75 .45 –0.104 –0.191, –0.017 –2.34 .02
Light_pct –0.032 –0.064, –0.001 –2.02 .04 0.090 –0.057, 0.237 1.20 .23
REM_pct 0.003 –0.021, 0.027 0.25 .80 –0.125 –0.238, –0.012 –2.17 .03
NREM_pct –0.038 –0.062, –0.014 –3.12 .002 –0.014 –0.127, 0.098 –0.25 .80
Awake_pct 0.035 0.022, 0.048 5.45 <.001 0.139 0.079, 0.199 4.58 <.001
Av_onset 0.007 –0.001, 0.015 1.71 .09 0.078 0.040, 0.115 4.03 <.001
Av_offset 0.025 0.017, 0.033 6.19 <.001 0.097 0.060, 0.135 5.10 <.001
REM_L 0.034 –0.021, 0.088 1.21 .23 0.085 –0.178, 0.347 0.63 .53
Std_tst 0.008 0.004, 0.012 4.07 <.001 0.047 0.028, 0.067 4.77 <.001
Std_onset 0.012 0.004, 0.019 3.11 .002 0.060 0.022, 0.097 3.13 .002
Std_offset 0.012 0.005, 0.018 3.58 <.001 0.069 0.037, 0.100 4.26 <.001
Efficiency –0.025 –0.037, –0.012 –3.91 <.001 –0.108 –0.167, –0.050 –3.65 <.001
Awake_5 0.016 0.010, 0.022 5.53 <.001 0.038 0.011, 0.065 2.77 .006
WKD_diff 0.134 0.039, 0.230 2.76 .006 0.747 0.255, 1.240 2.98 .003
M_insomnia 0.370 0.211, 0.530 4.55 <.001 2.373 1.595, 3.151 5.98 <.001
Dur_10 0.309 0.195, 0.423 5.30 <.001 0.909 0.357, 1.462 3.23 .001

aDefinitions of sleep features in this table are shown in Table 1.

bSleep subscore represents the score of subitem 3 in the PHQ-8.

cPHQ-8: Patient Health Questionnaire 8-item.

dSlope coefficient estimates for all sleep features.