Table 6.
Coefficient estimates, 95% confidence intervals, and P values from 2-level linear mixed models on the 3 study sites for exploring associations between sleep featuresa and the sleep subscoreb.
| Features | KCLc | CIBERd | VUmce | ||||||||
|
|
Coeff.f | 95% CI | P value | Coeff. | 95% CI | P value | Coeff. | 95% CI | P value | ||
| Av_tst | 0.015 | –0.021, 0.050 | .41 | –0.035 | –0.116, 0.047 | .41 | –0.017 | –0.070, 0.035 | .52 | ||
| Av_time_bed | 0.026 | –0.013, 0.066 | .19 | –0.025 | –0.116, 0.065 | .58 | –0.015 | –0.074, 0.043 | .61 | ||
| Deep_pct | –0.027 | –0.134, 0.081 | .63 | –0.196 | –0.412, 0.020 | .07 | –0.191 | –0.369, –0.014 | .04 | ||
| Light_pct | –0.024 | –0.213, 0.166 | .81 | 0.098 | –0.250, 0.445 | .58 | 0.312 | 0.016, 0.608 | .04 | ||
| REM_pct | –0.116 | –0.260, 0.028 | .12 | –0.037 | –0.304, 0.230 | .79 | –0.169 | –0.398, 0.060 | .15 | ||
| NREM_pct | –0.048 | –0.194, 0.098 | .52 | –0.123 | –0.389, 0.143 | .37 | 0.125 | –0.096, 0.346 | .27 | ||
| Awake_pct | 0.165 | 0.085, 0.245 | <.001 | 0.150 | 0.020, 0.280 | .02 | 0.049 | –0.073, 0.170 | .43 | ||
| Av_onset | 0.055 | 0.008, 0.101 | .02 | 0.075 | –0.023, 0.172 | .13 | 0.128 | 0.054, 0.202 | .001 | ||
| Av_offset | 0.102 | 0.053, 0.150 | <.001 | 0.048 | –0.040, 0.135 | .29 | 0.133 | 0.056, 0.210 | .001 | ||
| REM_L | 0.073 | –0.255, 0.401 | .66 | 0.146 | –0.494, 0.787 | .65 | –0.171 | –0.683, 0.340 | .51 | ||
| Std_tst | 0.046 | 0.022, 0.071 | <.001 | 0.046 | –0.002, 0.094 | .06 | 0.043 | 0.004, 0.082 | .03 | ||
| Std_onset | 0.028 | –0.015, 0.070 | .21 | 0.089 | –0.018, 0.195 | .10 | 0.079 | 0.020, 0.139 | .01 | ||
| Std_offset | 0.046 | 0.008, 0.084 | .02 | 0.109 | 0.022, 0.195 | .01 | 0.072 | 0.016, 0.127 | .01 | ||
| Efficiency | –0.118 | –0.196, –0.041 | .003 | –0.152 | –0.280, –0.024 | .02 | –0.044 | –0.162, 0.074 | .46 | ||
| Awake_5 | 0.047 | 0.011, 0.083 | .01 | 0.037 | –0.022, 0.097 | .22 | 0.013 | –0.042, 0.067 | .65 | ||
| WKD_diff | 1.169 | 0.534, 1.804 | <.001 | 0.210 | –0.864, 1.284 | .70 | 0.283 | –0.830, 1.395 | .62 | ||
| M_insomnia | 2.302 | 1.274, 3.329 | <.001 | 2.777 | 1.070, 4.485 | .001 | 1.823 | 0.180, 3.465 | .03 | ||
| Dur_10 | 1.057 | 0.387, 1.728 | .002 | 0.576 | –0.844, 1.995 | .43 | 0.706 | –0.411, 1.823 | .22 | ||
aThe definitions of sleep features in this table are shown in Table 1.
bThe sleep subscore represents the score of subitem 3 in the PHQ-8.
cKCL: King’s College London.
dCIBER: Centro de Investigación Biomédican en Red.
eVUmc: Vrije Universiteit Medisch Centrum.
fSlope coefficient estimates for all sleep features.