Table 3.
Comparison of each spectral power between each antipsychotic drug group and drug-free patients
| Lead | F3 | F4 | C3 | C4 | P3 | P4 | O1 | O2 |
|---|---|---|---|---|---|---|---|---|
| Free | ||||||||
| Delta | 53.6 ± 2.7 | 53.6 ± 2.5 | 51.8 ± 2.4 | 52.0 ± 2.5 | 51.4 ± 2.4 | 51.7 ± 2.4 | 51.7 ± 2.8 | 51.7 ± 2.8 |
| Theta | 48.1 ± 2.6 | 48.3 ± 2.4 | 47.4 ± 2.6 | 47.4 ± 2.7 | 47.2 ± 2.7 | 47.4 ± 2.7 | 47.3 ± 3.2 | 47.3 ± 3.3 |
| Alpha | 46.8 ± 2.4 | 46.9 ± 2.4 | 46.7 ± 2.4 | 46.9 ± 2.5 | 47.9 ± 3.1 | 48.2 ± 3.0 | 49.2 ± 3.8 | 49.2 ± 3.9 |
| Beta | 41.2 ± 2.5 | 41.5 ± 2.6 | 40.8 ± 2.3 | 41.1 ± 2.3 | 40.8 ± 2.2 | 41.1 ± 2.2 | 41.2 ± 2.4 | 41.2 ± 2.5 |
| Gamma | 34.0 ± 6.3 | 34.2 ± 5.9 | 33.4 ± 6.2 | 33.0 ± 5.4 | 32.0 ± 4.2 | 32.0 ± 4.2 | 32.4 ± 3.7 | 32.3 ± 3.9 |
| ARP | ||||||||
| Delta | 52.9 ± 2.2 | 52.9 ± 1.9 | 52.2 ± 2.0 | 52.7 ± 2.0 | 52.8 ± 2.0 | 53.2 ± 2.0 | 53.8 ± 3.0 | 53.4 ± 2.5 |
| Theta | 50.0 ± 2.6 | 50.2 ± 2.6 | 49.8 ± 2.6 | 50.2 ± 2.9 | 50.0 ± 2.8 | 50.2 ± 3.1 | 50.6 ± 3.4 | 50.3 ± 3.7 |
| Alpha | 49.3 ± 3.4 | 49.4 ± 3.2 | 49.4 ± 3.2 | 49.7 ± 3.2 | 50.5 ± 3.6 | 50.4 ± 3.8 | 52.3 ± 4.7 | 52.0 ± 5.1 |
| Beta | 41.1 ± 1.7 | 41.2 ± 1.7 | 40.9 ± 1.6 | 41.2 ± 1.8 | 41.2 ± 2.0 | 41.4 ± 2.0 | 42.1 ± 3.0 | 41.9 ± 3.3 |
| Gamma | 29.9 ± 3.8 | 31.2 ± 3.9 | 29.1 ± 3.2 | 29.6 ± 3.6 | 29.0 ± 2.8 | 29.1 ± 3.1 | 29.5 ± 2.9 | 29.8 ± 3.4 |
| RIS | ||||||||
| Delta | 51.5 ± 2.7 | 51.4 ± 2.2 | 50.4 ± 1.4 | 50.4 ± 1.0 | 50.1 ± 1.0 | 50.4 ± 1.2 | 50.1 ± 1.8 | 50.5 ± 2.3 |
| Theta | 49.4 ± 1.5 | 49.2 ± 1.4 | 49.2 ± 1.4 | 49.0 ± 1.3 | 49.0 ± 1.6 | 49.1 ± 1.5 | 48.7 ± 2.2 | 49.6 ± 2.6 |
| Alpha | 49.6 ± 2.4 | 49.7 ± 2.5 | 50.3 ± 2.5* | 50.6 ± 2.6* | 51.6 ± 2.5 | 51.8 ± 2.7 | 52.1 ± 3.0 | 52.9 ± 3.1 |
| Beta | 43.9 ± 2.6 | 44.0 ± 2.7 | 44.1 ± 2.1* | 44.7 ± 2.4* | 44.2 ± 2.3* | 44.3 ± 2.2* | 43.5 ± 2.6 | 43.9 ± 2.6 |
| Gamma | 35.2 ± 3.7 | 35.4 ± 5.3 | 33.3 ± 3.9 | 35.7 ± 6.1 | 32.7 ± 2.9 | 33.6 ± 3.8 | 33.4 ± 2.7 | 33.7 ± 3.0 |
| CLZ | ||||||||
| Delta | 55.7 ± 1.9 | 55.1 ± 2.5 | 54.2 ± 1.5 | 53.9 ± 1.6 | 54.0 ± 1.9 | 54.1 ± 2.2 | 52.1 ± 3.2 | 52.0 ± 2.9 |
| Theta | 53.9 ± 2.6 | 53.6 ± 3.0 | 52.7 ± 2.8 | 52.9 ± 2.9* | 51.7 ± 2.6* | 52.1 ± 3.1* | 49.9 ± 3.2 | 49.1 ± 4.1 |
| Alpha | 48.2 ± 1.9 | 47.9 ± 1.3 | 47.8 ± 1.4 | 48.0 ± 1.2 | 48.1 ± 1.2 | 47.8 ± 1.2 | 47.3 ± 1.8 | 46.1 ± 1.9 |
| Beta | 39.5 ± 3.4 | 39.6 ± 2.7 | 39.4 ± 2.8 | 39.8 ± 2.5 | 39.2 ± 2.2 | 39.4 ± 2.0 | 38.8 ± 2.0 | 38.9 ± 2.0 |
| Gamma | 27.3 ± 2.9 | 27.5 ± 2.3 | 27.0 ± 2.6 | 26.9 ± 2.1 | 28.3 ± 2.9 | 27.8 ± 2.2 | 29.1 ± 3.4 | 30.8 ± 4.0 |
| OLZ | ||||||||
| Delta | 59.1 ± 4.2 | 58.8 ± 3.8 | 56.8 ± 4.5 | 57.0 ± 4.3 | 56.8 ± 3.9* | 57.0 ± 3.5* | 56.7 ± 4.7 | 57.0 ± 5.0 |
| Theta | 53.0 ± 3.4 | 52.5 ± 3.2 | 51.6 ± 2.5 | 51.4 ± 2.9 | 51.0 ± 3.2 | 51.0 ± 3.2 | 50.6 ± 3.8 | 50.4 ± 4.1 |
| Alpha | 50.3 ± 4.9 | 50.2 ± 4.5 | 50.0 ± 3.8 | 50.0 ± 3.9 | 50.6 ± 5.5 | 50.3 ± 5.1 | 51.2 ± 6.1 | 51.1 ± 6.6 |
| Beta | 44.7 ± 3.6 | 44.8 ± 3.5 | 44.6 ± 3.5 | 44.3 ± 3.2 | 44.5 ± 3.8 | 44.2 ± 3.7 | 44.9 ± 3.6 | 45.1 ± 3.9 |
| Gamma | 37.0 ± 4.5 | 36.1 ± 4.8 | 35.2 ± 6.2 | 34.0 ± 6.4 | 34.0 ± 3.9 | 33.8 ± 4.2 | 35.3 ± 3.8 | 36.0 ± 3.8 |
| BNS | ||||||||
| Delta | 55.4 ± 3.9 | 55.3 ± 4.5 | 53.6 ± 5.0 | 53.4 ± 5.0 | 53.7 ± 3.8 | 53.9 ± 4.4 | 54.3 ± 5.9 | 53.7 ± 5.2 |
| Theta | 50.4 ± 3.5 | 50.6 ± 3.4 | 49.7 ± 3.9 | 49.6 ± 3.6 | 49.5 ± 3.8 | 49.6 ± 4.1 | 49.6 ± 5.6 | 49.3 ± 5.3 |
| Alpha | 49.1 ± 2.7 | 49.3 ± 3.0 | 49.4 ± 2.8 | 49.2 ± 2.7 | 51.3 ± 3.7 | 50.8 ± 3.6 | 53.9 ± 5.5 | 53.0 ± 5.1 |
| Beta | 42.0 ± 2.7 | 42.0 ± 2.7 | 42.2 ± 2.7 | 42.0 ± 2.9 | 43.5 ± 2.9 | 42.9 ± 3.0 | 44.7 ± 4.4 | 44.5 ± 3.9 |
| Gamma | 33.6 ± 1.9 | 32.4 ± 1.3 | 32.1 ± 1.2 | 31.8 ± 1.4 | 32.4 ± 2.0 | 31.9 ± 1.9 | 34.4 ± 2.7 | 33.9 ± 2.9 |
Each value represents the mean regional absolute power in mV2 ± standard deviation.
Free: drug-free patients. ARP, aripiprazole; RIS, risperidone; CLZ, clozapine; OLZ, olanzapine; BNS, blonanserin.
pvalue represents the significance of differences in spectral power between drug-free patients and each antipsychotic drug group (*p < 0.05). A Mann−Whitney Utest with a Dunn correction were used to adjust the pvalues for multiple comparisons.