Table 2.

Odds ratios and 95% confidence intervals for each condition improving or resolving comparing those who reduce drinking (AUDIT<8) at 1-year with those who do not reduce drinking (AUDIT≥8) at 1-year

Condition improves	Analysis	Odds ratios* (95% CIs)
		At 1-year	At 2-years
Current moderate or severe pain	Unadjusted	1.45 (0.97, 2.17)	1.89 (1.20, 2.99)
Interference symptoms	Adjusted	1.31 (0.84, 2.07)	1.49 (0.91, 2.42)
Current smoking	Unadjusted	2.10 (1.28, 3.44)	1.64 (1.01, 2.68)
	Adjusted	1.67 (0.98, 2.84)	1.57 (0.93, 2.63)
Current depressive symptoms	Unadjusted	1.18 (0.76, 1.82)	1.33 (0.80, 2.22)
	Adjusted	1.10 (0.68, 1.79)	1.11 (0.64, 1.92)
Current anxiety symptoms	Unadjusted	1.03 (0.73, 1.45)	1.38 (0.86, 2.22)
	Adjusted	1.33 (0.82, 2.15)	1.33 (0.80, 2.22)
Past year cannabis use	Unadjusted	--	1.66 (1.00, 2.76)
	Adjusted	--	1.65 (0.92, 2.95)
Past year cocaine use	Unadjusted	--	2.05 (1.24, 3.37)
	Adjusted	--	1.83 (1.03, 3.27)

^*Adjusted for HIV status, race, education, income, baseline conditions (AUDIT score, depressive symptoms, anxiety symptoms, moderate or severe pain interference symptoms, current smoking, and past-year cannabis, cocaine, other stimulant, and illicit opioid use), and time-varying covariates measured at 1-year (past-year cannabis, cocaine, other stimulant, and illicit opioid use).

^--Cannot evaluate “past year” outcomes at 1-year since exposure is “past year” alcohol.