Table 4.

Odds ratios and 95% confidence intervals for each condition improving or resolving at 2-years post-baseline comparing those who reduce drinking (AUDIT<8) at 1-year with those who do not reduce drinking (AUDIT≥8) at 1-year, by HIV-status

Condition improves	Odds ratios* (95% CIs)
	HIV-negative	HIV-positive
Current moderate or severe pain interference symptoms	2.03 (1.07, 3.85)	0.93 (0.43, 2.03)
Current smoking	0.86 (0.40, 1.85)	2.44 (1.18, 5.03)
Current depressive symptoms	1.00 (0.45, 2.21)	1.15 (0.53, 2.53)
Current anxiety symptoms	1.21 (0.57, 2.56)	1.38 (0.68, 2.80)
Past year cannabis use	2.25 (0.86, 5.87)	1.36 (0.65, 2.84)
Past year cocaine	1.42 (0.56, 3.62)	2.12 (1.02, 4.43)

^*Adjusted for, race, education, income, baseline conditions (AUDIT score, depressive symptoms, anxiety symptoms, moderate or severe pain interference symptoms, current smoking, and past-year cannabis, cocaine, other stimulant, and illicit opioid use), and time-varying covariates measured at 1-year. For simplicity, we show one time point only. The DAG could be extended to include time zero and time two.