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. 2021 Apr 23;218(6):e20210008. doi: 10.1084/jem.20210008

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© 2021 Li et al.

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Figure S1. — Netrin-1 levels showed no differences in murine IR heart tissue and blood of female/male subgroups. (A and B) Murine heart tissue netrin-1 levels were measured in sham and IR2h groups with Western blot analysis. Quantifications showed netrin-1 levels in heart tissue did not change significantly after 45 min of ischemia and 2 h of reperfusion (n = 5 for each group; two-tailed unpaired t test). (C and D) Murine IR injury model shows no significant differences of blood netrin-1 levels between female and male mice in both sham and IR groups (n = 3 per sham group, n = 5 for female IR group, and n = 4 for male IR group; two-tailed unpaired t test). Data are presented as mean ± SD.