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. 2021 Apr 23;218(6):e20210008. doi: 10.1084/jem.20210008

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© 2021 Li et al.

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Figure S5. — Netrin-1 reduces neutrophil transmigration, which is ADORA2B dependent. (A) Murine neutrophil transmigration assay results show NTN1 reduces murine neutrophil transmigration and ADORA2B receptor antagonist PSB1115 abolishes the effect (n = 4 per group; one-way ANOVA with Bonferroni post hoc tests). Data from four independent experiments. (B and C) Human neutrophil transmigration assay 1-h (B) and 2-h (C) results show NTN1 reduces human neutrophil transmigration and ADORA2B receptor antagonist PSB1115 abolishes the effect (n = 4 per group; one-way ANOVA with Bonferroni post hoc tests). **, P < 0.01; ***, P < 0.001. Data are presented as mean ± SD. Data from four independent experiments.