Table 3.
Unique differentially altered miRNAs in spontaneous Hepatocellular carcinomas compared to age-matched control liver
| Transcript ID | Symbol | Fold change | Adjusted p-value |
|---|---|---|---|
| Unique downregulated miRNA (n=10) | |||
| mmu-miR-193 | miR-193a-3p (and other miRNAs w/seed ACUGGCC) | −5.98 | 0.00136324 |
| mmu-miR-5132 | miR-5132–5p (miRNAs w/seed CGUGGGG) | −5.03 | 0.0468464 |
| mmu-miR-203 | miR-203a-3p (and other miRNAs w/seed UGAAAUG) | −4.97 | 0.04142236 |
| mmu-miR-10a | miR-10a-5p (and other miRNAs w/seed ACCCUGU) | −4.54 | 0.03940415 |
| mmu-miR-22-star | miR-22–5p (and other miRNAs w/seed GUUCUUC) | −4.18 | 0.00993676 |
| mmu-miR-193-star | miR-193a-5p (miRNAs w/seed GGGUCUU) | −2.63 | 0.00700403 |
| mmu-miR-378-star | miR-378a-5p (miRNAs w/seed UCCUGAC) | −2.45 | 0.01446302 |
| mmu-miR-378b | miR-378b (and other miRNAs w/seed UGGACUU) | −2.35 | 0.01085118 |
| mmu-miR-341-star | miR-341–5p (miRNAs w/seed GGUCGGC) | −2.17 | 0.03763051 |
| mmu-miR-802 | miR-802–5p (miRNAs w/seed CAGUAAC) | −2.06 | 0.0127478 |
| Unique upregulated miRNA (n=8) | |||
| mmu-miR-146b | miR-146a-5p (and other miRNAs w/seed GAGAACU) | 92.32 | 4.45E-06 |
| mmu-miR-193b | miR-193a-3p (and other miRNAs w/seed ACUGGCC) | 9.24 | 0.01446302 |
| mmu-miR-182 | miR-182–5p (and other miRNAs w/seed UUGGCAA) | 8.84 | 0.03020976 |
| mmu-miR-210 | miR-210–3p (miRNAs w/seed UGUGCGU) | 4.88 | 0.03940415 |
| mmu-miR-99b | miR-100–5p (and other miRNAs w/seed ACCCGUA) | 3.56 | 0.00909049 |
| mmu-miR-574–3p | miR-574–3p (miRNAs w/seed ACGCUCA) | 2.96 | 0.0212642 |
| mmu-miR-674 | miR-674–5p (and other miRNAs w/seed CACUGAG) | 2.27 | 0.01377644 |
| mmu-miR-320 | miR-320b (and other miRNAs w/seed AAAGCUG) | 2.07 | 0.00909049 |