Table 5.
Differentially expressed miRNAs and corresponding differentially expressed targeted genes in GBE-HCC and SPNT-HCC. Statistical analysis identified significant correlations at the adjusted p-value of 0.05 and fold change of 2 for both miRNA and mRNA expression levels. DmiRs: Differentially expressed miRNAs, FDR: False discovery rate, FC: Fold change
| GBE-HCC | SPNT-HCC | Common | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Total DmiRs-Targets | Downregulated miRNA-Targets | Upregulated miRNA-Targets | Total DmiRs-Targets | Downregulated miRs-Targets | Upregulated miRs-targets | Total DmiRs-Targets | Downregulated miRs-Targets | Upregulated miRs-targets | |
| miRNA | 59 | 14 | 45 | 18 | 10 | 8 | 15 | 8 | 7 |
| miRNA with targets | 40 | 7 | 33 | 15 | 8 | 7 | 9 | 3 | 6 |
| FDR 0.05, FC 2 | 576 | 202 | 508 | 332 | 211 | 204 | 383 | 116 | 296 |
| Up regulation in mRNA | 383 | 138 | 337 | 214 | 130 | 134 | |||
| Downregulation in mRNA | 193 | 64 | 171 | 118 | 81 | 70 | |||