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. 2020 Jun 30;105(5):723–728. doi: 10.1136/bjophthalmol-2020-316594

Table 4.

Screening performance measures along with 95% confidence limits for each centre and for all three centres combined

Final human grade Percentage classified as test-positive (including technical failure) by EyeArt (95% CI)*
NEL GS SEL Combined
R0M0 31.9 (30.8, 33.0) 28.8 (27.7, 29.9) 35.4 (34.3, 36.4) 32.1 (31.5, 32.7)
R1M0 91.8 (90.6, 92.9) 83.7 (82.2, 85.1) 93.3 (92.1, 94.3) 89.1 (88.4, 89.9)
R1M1 98.9 (97.1, 99.6) 97.2 (94.5, 98.6) 98.6 (96.6, 99.4) 98.3 (97.3, 98.9)
R2* 100.0 (97.1, 100.0) 100.0 (92.9, 100.0) 100.0 (96.8, 100.0) 100.0 (98.7, 100.0)
 R2M0 100.0 (90.7, 100.0) 100.0 (85.8, 100.0) 100.0 (88.8, 100.0) 100.0 (96.1, 100.0)
 R2M1 100.0 (95.9, 100.0) 100.0 (86.8, 100.0) 100.0 (95.6, 100.0) 100.0 (98.1, 100.0)
R3* 100.0 (93.7, 100.0) 100.0 (92.7, 100.0) 100.0 (94.6, 100.0) 100.0 (97.9, 100.0)
 R3M0 100.0 (87.7, 100.0) 100.0 (85.2, 100.0) 100.0 (83.2, 100.0) 100.0 (94.9, 100.0)
 R3M1 100.0 (88.1, 100.0) 100.0 (86.8, 100.0) 100.0 (92.3, 100.0) 100.0 (96.4, 100.0)
U 90.4 (86.5, 93.3) 88.6 (83.2, 92.4) 88.9 (84.3, 92.3) 89.4 (87.0, 91.5)

*95% CIs are binomial exact.

Retinopathy grades: No retinopathy (R0); mild-to-moderate non-proliferative retinopathy (R1); non-referable maculopathy (M0); ungradable images (U); referable maculopathy (M1), moderate-to-severe non-proliferative retinopathy (R2) and proliferative retinopathy (R3).8 9

GS, Gloucestershire; NEL, North East London; SEL, South East London.