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. Author manuscript; available in PMC: 2021 Apr 27.
Published in final edited form as: Endocrine. 2019 Jul 19;65(3):692–706. doi: 10.1007/s12020-019-02008-6

Fig. 3.

Fig. 3

Changes in Total and Appendicular lean mass (%) With Testosterone Therapy According to rs1062033 and rs700518 Polymorphisms. Total lean mass significantly increased in the CC genotype compared to the CG and GG genotypes at 18 months (a); and appendicular lean mass significantly increased in the CC compared to the CG genotype at 12 months and compared to the GG genotype at 18 months (b) in the rs1062033 polymorphism. There were increases in total lean mass in all the genotypes but significantly higher for the AA genotype of the rs700518 polymorphism compared to AG at 6 months, and compared to both AG and GG at 12 and 18 months (c). There were are also increases in appendicular lean mass in all the genotypes which was sustained to a certain degree in the AA and AG genotypes but not in the GG genotype (d). The increase in appendicular lean mass in the AA genotype was significantly higher compared to the AG genotype at 6 months, to both AG and GG genotypes at 12 months, and to the GG genotype at 18 months (d). All P values adjusted for age and body mass index. ap < 0.05 CC vs. CG, bp < 0.05 CC vs. GG, cp < 0.05 AA vs. AG, dp < 0.05 AA vs. GG.