Table 2.
Detectable lectins and glycans on TgAb IgG1 via lectin microarray
Abbreviation | Full name | Specificity | |
---|---|---|---|
1 | PSA | Pisum sativum agglutinin | αMan, αGlc |
2 | LCA | Lens culinaris agglutinin | α-D-mannose, α-D-glucose |
3 | AAL | Aleuria aurantia lectin | Fucα6GlcNAc |
4 | LAL | Laburnum anagyroides lectin (gold chain) | best inhibitor is alpha-Me-L-fucose among monosaccharides |
5 | SNA/EBL | Sambucus nigra lectin | Neu5Acα6Gal/GalNAc |
6 | SNA-I | Sambucus nigra agglutinin I (elderberry bark) | alpha 2,6 linked sialic acid residues |
7 | ConA | concanavalin A lectin | αMan, αGlc |
8 | MNA-M | Morniga M lectin (black elderberry) | Man |
9 | Black bean crude | Phaseolus vulgaris sp. lectin | GalNAc > lactose > galactose, sialic acid |
10 | IRA | Iris hybrid lectin (Dutch iris) | N-acetyl-D-galactosamine |
11 | HMA | Homarus americanus lectin (lobster) | αGalNAc, αFuc, Neu5Ac |
12 | RCAI/RCA120 | Ricinus communis agglutinin I | Gal |
IgG, immunoglobulin G; TgAb, thyroglobulin antibody.