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. Author manuscript; available in PMC: 2021 Apr 27.
Published in final edited form as: Ophthalmology. 2017 Sep 12;125(2):245–254. doi: 10.1016/j.ophtha.2017.08.008

Table 3.

Significantly Different Metabolites (P < 0.001) between Patients with Age-Related Macular Degeneration and Controls

Biochemical Superpathway Subpathway Metabolites in AMD Patients vs. Controls Odds Ratio* P Value
Linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2]* Lipid Diacylglycerol Decreased 0.0961 0.0008
Stearoyl-arachidonoyl-glycerol (18:0/20:4) [1]* Lipid Diacylglycerol Decreased 0.0411 0.0009
Oleoyl-arachidonoyl-glycerol (18:1/20:4) [2]* Lipid Diacylglycerol Decreased 0.0463 0.0002
Oleoyl-arachidonoyl-glycerol (18:1/20:4) [1]* Lipid Diacylglycerol Decreased 0.111 0.0007
1-Palmitoyl-2-arachidonoyl-GPC (16:0/20:4n6) Lipid Phosphatidylcholine Decreased 0.0004 0.0006
1-Stearoyl-2-arachidonoyl-GPC (18:0/20:4) Lipid Phosphatidylcholine Decreased 0.0002 0.0005
Adenosine Nucleotide Purine metabolism, adenine containing Increased 3.7422 0.0009

AMD = age-related macular degeneration; GPC = glycero-3-phosphocholine; PC = phosphatidylcholine.

*

Reference term for odds ratios is the control group, which means that values of less than 1 represent a decrease in patients with age-related macular degeneration as compared with controls (and the opposite for values of more than 1).