SPADE trees and annotations for the peripheral blood (PB) of normal
donors and cancer patients, and cancer patients spleens for all three flow
panels (CTLA-4, PD-L1, and enzyme); reported as cell frequency from exported
total MDSC population. Annotations 1–5 are representative of cell
clusters consistently found for all sample types (Table 3). Annotations 6–12, 13–18, and
19–24 (Table 4) are representative
of MDSC subpopulations identified in each sample type and source for flow panels
CTLA-4, PD-L1, and enzyme respectively.