Numerically denoted phenotypic marker expression from CytoBackBone
analysis of the myeloid derived suppressor cell (MDSC) subpopulations in the
peripheral blood (PB) of normal donors and cancer patients, and cancer
patients’ spleens (Fig. 6).
Annotations 1–4 are representative of clusters consistently identified in
all sample types and sources (Table 5). Annotations 5–12,
13–20, and 21–30 are representative of MDSC subpopulations
identified in the PB of normal donors, and the PB and spleen cells of cancer
patients, respectively (Table 5). Relative phenotypic marker
expression is shown for the merged CTLA-4 and PD-L1 flow panels and ranges from
low (blue) to high (red). The median and range of the phenotypic marker
expression can be references in ST 4.