TABLE 3.
ADHD-RS-IV total and subscale score changes during the study and subgroup analyses stratified by age group (children and adolescents)
| Subgroup | V1 (previous MPH treatment) | Δ V2 – V1 | Δ V3 – V1 | |||||
|---|---|---|---|---|---|---|---|---|
| N | Mean ± SD | N | Mean ± SD | p | N | Mean ± SD | p | |
| Total population | ||||||||
| ADHD-RS-IV total score | 136 | 27.1 ± 11.7 | 96 | -11.9 ± 10.8 | < .001 | 85 | -12.7 ± 10.9 | < .001 |
| ADHD-RS-IV subscale hyperactivity/impulsivity | 136 | 11.1 ± 7.3 | 96 | -5.0 ± 6.1 | < .001 | 85 | -5.7 ± 5.8 | < .001 |
| ADHD-RS-IV subscale inattention | 136 | 16.0 ± 5.4 | 97 | -6.8 ± 5.6 | < .001 | 85 | -7.1 ± 5.9 | < .001 |
| Subgroup analysis according to age group | ||||||||
| ADHD-RS-IV total score | ||||||||
| Children | 80 | 27.7 ± 12.9 | 58 | -11.7 ± 11.7 | < .001 | 54 | -12.8 ± 11.3 | < .001 |
| Adolescents | 56 | 26.2 ± 9.8 | 38 | -12.1 ± 9.3 | < .001 | 31 | -12.5 ± 10.3 | < .001 |
| ADHD-RS-IV subscale hyperactivity/impulsivity | ||||||||
| Children | 80 | 11.8 ± 8.2 | 58 | -5.0 ± 6.8 | < .001 | 54 | -6.0 ± 6.0 | < .001 |
| Adolescents | 56 | 10.0 ± 5.6 | 38 | -5.1 ± 4.9 | < .001 | 31 | -5.1 ± 5.4 | < .001 |
| ADHD-RS-IV subscale inattention | ||||||||
| Children | 80 | 15.9 ± 5.7 | 59 | -6.7 ± 5.6 | < .001 | 54 | -6.9 ± 6.0 | < .001 |
| Adolescents | 56 | 16.1 ± 5.1 | 38 | -7.0 ± 5.6 | < .001 | 31 | -7.4 ± 5.9 | < .001 |
Notes. MPH: Methylphenidate; N: Number of patients; SD: Standard deviation
Only complete ADHD total scores were used; p-value based on t-test for paired samples