Table 1.
Proposed antibiotic dosage (based on guidelines published by the American Urological Association, Canadian Urological Association, Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, and the European Urological Society)
| Indication | Antibiotic | Dosage | Treatment duration |
|---|---|---|---|
| Prophylaxis in asymptomatic bacteriuria; continuous treatment | Trimethoprim | 100 mg 1× a day | |
| Trimethoprim + sulfamethoxazole | 40–200 mg 1× a day 40–200 mg 3× a week |
||
| Nitrofurantoin | 50–100 mg a day | ||
| Cephalexin | 125–250 mg 1x a day | ||
| Fosfomycin | 3 γ every 10 days | ||
| Prophylaxis in asymptomatic bacteriuria; periodic treatment | Trimethoprim + sulfamethoxazole | 40/200 mg 80/400 mg |
|
| Nitrofurantoin | 50–100 mg | ||
| Cephalexin | 250 mg | ||
| Uncomplicated cystitis | Fosfomycin | 3 g | For 1 day |
| Nitrofurantoin | 50–100 mg a day | For 5 days | |
| Extended-release nitrofurantoin | 100 mg 2× a day | For 5 days | |
| Pivampicillin | 400 mg 3× a day | For 3–5 days | |
| Cephalosporins | 500 mg 2× a day | For 3 days | |
| Trimethoprim + sulfamethoxazole | 80/400 mg 2× a day | For 3 days | |
| Trimethoprim | 100 mg 2× a day | For 3–5 days | |
| Complicated cystitis | Ciprofloxacin | 500–750 mg 2× a day | For 7 days |
| Levofloxacin | 750 mg a day | For 5 days | |
| Trimethoprim + sulfamethoxazole | 160/800 mg 2× a day | For 14 days | |
| Cefpodoxime | 200 mg 2× a day | For 10 days | |
| Ceftibuten | 400 mg a day | For 10 days | |
| Pyelonephritis, parenteral therapy 1st line of treatment |
Ciprofloxacin | 400 mg 2× a day | |
| Levofloxacin | 750 mg a day | ||
| Cefotaxime | 2 γ 3x a day | ||
| Ceftriaxone | 1–2 γ a day | ||
| Pyelonephritis, parenteral therapy 2nd line of treatment |
Cefepime | 1–2 γ 2× a day | |
| Piperacillin/tazobactam | 2.5–4.5 γ 3× a day | ||
| Gentamycin | 5 mg/kg a day | ||
| Amikacin | 15 mg/kg a day |
Not all antibiotics are available in Poland.