Skip to main content
. 2021 Apr 13;12:641888. doi: 10.3389/fendo.2021.641888

Table 1.

Pathways common between T2D and obesity and specific to T2D and obesity (Venn diagram outcome).

Name Total Pathways
T2D and Obese 14 Cell adhesion molecules (CAMs); PI3K-Akt signaling pathway; cAMP signaling pathway; Phospholipase D signaling pathway; Focal adhesion; Hematopoietic cell lineage; Rap1 signaling pathway; Tight junction; Leukocyte transendothelial migration; Phagosome; MAPK signaling pathway; ECM-receptor interaction; Regulation of actin cytoskeleton; Ras signaling pathway
T2D 17 Neurotrophin signaling pathway; Insulin signaling pathway; Vascular smooth muscle contraction; Sphingolipid signaling pathway; cGMP-PKG signaling pathway; mTOR signaling pathway; T cell receptor signaling pathway; Natural-killer-cell-mediated cytotoxicity; Jak-STAT signaling pathway; Progesterone-mediated oocyte maturation; B cell receptor signaling pathway; Oxytocin signaling pathway; Platelet activation; Thyroid hormone signaling pathway; Wnt signaling pathway; ErbB signaling pathway; Ubiquitin mediated proteolysis
Obese 18 Fatty acid metabolism; Cell cycle; Tyrosine metabolism; Thyroid hormone synthesis; Starch and sucrose metabolism; Purine metabolism; Cytokine-cytokine receptor interaction; Metabolism of xenobiotics by cytochrome P450; Retinol metabolism; Drug metabolism - cytochrome P450; Neuroactive ligand-receptor interaction; Tryptophan metabolism; p53 signaling pathway; Complement and coagulation cascades; Antigen processing and presentation; Arachidonic acid metabolism; Axon guidance; Retrograde endocannabinoid signaling