Methods |
Double‐blind RCT. Regular supplementation trial. Duration 2 weeks |
Participants |
Children attending ski school in Swiss Alps. 139 vitamin C; 140 placebo |
Interventions |
1 g/d vitamin C |
Outcomes |
Incidence (Analysis 1.1) and duration (Analysis 2.1) |
Notes |
SD for duration was not published and the SD was calculated from the P value |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Low risk |
Randomised |
Allocation concealment (selection bias) |
Low risk |
Double‐blind |
Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
Double‐blind |
Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Double‐blind |
Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
|
Vitamin C and placebo indistinguishable? |
Low risk |
"The placebo was indistinguishable from the 1‐gm ascorbic acid tablet" |