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. 2016 Aug 18;2016(8):CD005282. doi: 10.1002/14651858.CD005282.pub3

Comparison 2. Fish oil versus statins.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Total cholesterol 2 75 Mean Difference (IV, Random, 95% CI) 0.36 [‐0.10, 0.82]
1.1 Fish oil (3 g) versus simvastatin (10 mg) 1 43 Mean Difference (IV, Random, 95% CI) 0.31 [‐0.31, 0.93]
1.2 Fish oil (0.6 g) versus lovastatin (20 mg) 1 32 Mean Difference (IV, Random, 95% CI) 0.42 [‐0.25, 1.09]
2 LDL cholesterol 2 75 Mean Difference (IV, Random, 95% CI) 0.41 [‐0.06, 0.88]
2.1 Fish oil (3 g) versus simvastatin (10 mg) 1 43 Mean Difference (IV, Random, 95% CI) 0.37 [‐0.19, 0.93]
2.2 Fish oil (0.6 g) versus lovastatin (20 mg) 1 32 Mean Difference (IV, Random, 95% CI) 0.51 [‐0.35, 1.37]
3 HDL cholesterol 2 75 Mean Difference (IV, Random, 95% CI) ‐0.18 [‐0.39, 0.02]
3.1 Fish oil (3 g) versus simvastatin (10 mg) 1 43 Mean Difference (IV, Random, 95% CI) ‐0.08 [‐0.30, 0.14]
3.2 Fish oil (0.6 g) versus lovastatin (20 mg) 1 32 Mean Difference (IV, Random, 95% CI) ‐0.29 [‐0.51, ‐0.07]
4 Triglycerides 2 75 Mean Difference (IV, Random, 95% CI) 0.18 [‐0.18, 0.55]
4.1 Fish oil (3 g) versus simvastatin (10 mg) 1 43 Mean Difference (IV, Random, 95% CI) 0.25 [‐0.17, 0.67]
4.2 Fish oil (0.6 g) versus lovastatin (20 mg) 1 32 Mean Difference (IV, Random, 95% CI) ‐0.02 [‐0.75, 0.71]